Human Tissue Distribution of Orally Supplemented Natural Vitamin E Tocotrienol

Chandan Sen, PhD Ohio State University

Completed

Objective:
Levels of tocotrienol in human tissues following supplementation is not currently known. The objective of this present study is to determine the levels of this form of vitamin E in the human tissues such as skin, heart, lung, liver, adipose tissue, brain and cerebrospinal fluid (CSF) following oral supplementation.

Study Type: Interventional

Study Design: Non-randomized, single-blind

Subjects: 1) Healthy volunteers 2) Patients requiring surgery

Intervention: Tocotrienol, Tocopherol

Primary Outcome:

  • Measure levels of tocotrienol in the tissues of “not-healthy” subjects and in the tissue of “healthy” subjects following oral supplementation (200 mg x 2 per day for 4-24 weeks) after at least 1 month of supplementation.

Methodology: Not available

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