A recent phase II clinical trial1 partially funded by ExcelVite (Chemor, Malaysia) found that a tocotrienol-rich vitamin E (EVNol SupraBio from ExcelVite) may support the conduction velocity of median and sural sensory nerves among type 2 diabetics. Diabetic peripheral neuropathy affects approximately 50% of type 2 diabetics in their lifetime. It causes nerve damage in patients that can lead to impaired mobility and quality of life.
Supplementation with annatto-derived delta-tocotrienol may improve glucose control, inflammation and oxidative stress in people with type 2 diabetes mellitus (T2DM), says a new study from the National University of Medical Sciences in Pakistan.
Delta-tocotrienol from annatto has been shown in a new clinical study to improve glycemic control, inflammation, and oxidative stress in patients diagnosed with type 2 diabetes mellitus, according to a press release from American River Nutrition.
The randomized, double-blind, placebo-controlled trial was published in Phytotherapy Research. It was performed on 110 patients with T2 diabetes. For 24 weeks, the patients received either a placebo or 250mg/day of DeltaGold tocotrienols. The participants were encouraged to perform regular physical activity, and continued using their typical hypoglycemic agents without insulin usage.
Back-to-basics As, Bs, and Cs (and Ds, and Ks, and Es) are basking in vitamins’ newfound glow.
Jia Zhang Lee, executive director, Davos Life Science (Singapore), notes that his company has seen a steady increase in demand for vitamin E tocotrienols in particular. “Research studies have shown that tocotrienols have positive health benefits in the management of hypertension, heart disease, and diabetes,” Lee notes. “These chronic conditions predispose individuals to the more severe form of COVID-19, and therefore there’s been growing interest in tocotrienol supplementation to help promote the prevention of these chronic diseases.”
Malaysian tocotrienol supplier Excelvite is working with supplement brands to promote the use of tocotrienol-rich vitamin E to pharmacists and doctors treating patients with diabetic kidney disease (DKD), on the back of new clinical findings.
The Malaysian Palm Oil Board (MPOB) has developed three advanced palm-based technologies for commercialisation.
In a statement on Friday, it said the first is the process and formulation of palm vitamin E/ tocotrienol-rich fraction (TRF) chewable tablet. The second is palm oil-based polyol for floor coverings for indoor and outdoor and sports flooring markets while the third is a moisturising hand sanitiser with Vitamin E. MPOB said the three are among the technologies approved by the Minister of Plantation Industries and Commodities for commercialisation.
Diabetic retinopathy (DR) is one of several diabetes related complications and now is the leading cause of new onset blindness among individuals aged 20–64 years old.In the study, Streptozotocin-induced diabetic rats were divided into two treatment groups based on the route of administration of treatment — oral treatment group and topical treatment group.
Vitamin E from red palm oil can reduce damage to the nerves, eyes and kidneys in people with diabetes, an endocrinologist has told FMT.
Dr Khalid Abdul Kadir of Monash University said he had found that nerve damage was reduced in diabetics who were given 400 mg per day of Vitamin E tocotrienols derived from palm oil.
A study on obese mice revealed a correlation between supplementing with tocotrienols and an increase in skeletal muscle weight and muscle fiber. These latest results were published recently in the Journal of Nutritional Biochemistry.
Vitamin E is a fat-soluble compound with antioxidant properties. Getting enough vitamin E is essential for the immune system, blood vessel health, and keeping the skin youthful.