Ongoing
Objectives: The following two objectives are proposed in healthy subjects to characterize (1) wound closure, (2) scar formation/appearance, and (3) inflammatory response:
Objective 1, (topical only – referred to as “TOP”) – Topical application of TCT vs placebo in bilateral punch biopsy
Objective 2, (oral and topical – referred to as “OTOP”) – Combined oral supplementation and topical application of TCT vs placebo in bilateral punch biopsy
Study Type: Observational
Study Design: Cohort Prospective Study
Subjects: Healthy volunteers
Intervention: Tocotrienol, placebo
Primary Outcome: Safety Issue
Methodology: Biospecimen Retention: Samples With DNA
Tissue biopsy will be collected twice in the study period.