Effect of a Palm-Oil Vitamin E Concentrate on the Serum and Lipoprotein Lipids in Humans

Tan DT, Khor HT, Low WH, Ali A, Gapor A.

Published

Objectives: To assess the effect of a capsulated palm-oil-vitamin E concentrate (Palmvitee) on human serum and lipoprotein lipids.

Subjects: Healthy volunteers

Intervention: Palm-oil vitamin E concentrate (18 mg tocotrienol)

Primary outcome: Serum lipids and lipoproteins

Methodology: All volunteers took one palmvitee capsule per day for 30 consecutive days. Overnight fasting blood was taken from each volunteer before and after the experiment. Serum lipids and lipoproteins were analyzed by using the enzymatic CHOD-PAP method.

Results: Our results showed that palmvitee lowered both serum total cholesterol (TC) and low-density-lipoprotein cholesterol (LDL-C) concentrations in all the volunteers. The magnitude of reduction of serum TC ranged from 5.0% to 35.9% whereas the reduction of LDL-C values ranged from 0.9% to 37.0% when compared with their respective starting values. Theeffect of palmvitee on triglycerides (TGs) and HDL-C was not consistent.

Conclusion: The results show that the palmvitee has a hypocholesterolemic effect.

Read More