Obesity and its consequences on overall health have become a serious global problem. However, very few substances or drugs can fight obesity. In a recent study, Japanese researchers investigated the anti-obesity effects of tocotrienols, a subtype of vitamin E. Experiments showed that tocotrienols significantly reduce the weight gained by mice on a high-fat diet, while also lowering “bad” cholesterol levels. The results pave the way to efficient treatments for obesity.