Tocotrienol exerts a synergistic effect with alpha-tocopherol on rat 
models of steatohepatitis (fatty liver). Results have shown that lipid peroxide levels in the liver are lower and signs of increased liver damage are controlled after combined intake of tocotrienol and alpha-tocopherol. High levels of inflammatory cytokines mRNA suppression were observed and particularly, the gamma-isoform of tocotrienol significantly inhibited mRNA expression of TGF-beta1.
